Frequent question: Is Lithium bad for pregnancy?

The risks to your baby with taking lithium while pregnant or breastfeeding are: Heart defects. Taking lithium in early pregnancy can increase the risk that your baby’s heart might not develop properly. Your doctor or midwife should monitor your baby’s heart using ultrasound scans.

Can lithium cause birth defects?

New York—The largest-ever study of birth defects in babies exposed to lithium found an elevated risk of major congenital malformations in fetuses after first-trimester exposure to the mental health drug.

Can lithium affect baby?

Lithium exposure is associated with increased risk of neonatal complications. Newport et al. found an association between high infant lithium concentrations and lower 1-min Apgar scores, higher rate of central nervous system and neuromuscular complications and longer duration of hospital stays (Newport et al. 2005).

Should lithium be stopped in pregnancy?

If a woman taking lithium becomes pregnant, consider stopping the medicine gradually over 4 weeks if she is well. Explain to her that: stopping medication may not remove the risk of fetal heart malformations. there is a risk of relapse, particularly in the postnatal period, if she has bipolar disorder.

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What risks are associated with lithium treatment during pregnancy?

There has been concern that exposure to lithium early in pregnancy may be associated with a marked increase in the risk of Ebstein’s anomaly (a right ventricular outflow tract obstruction defect) in infants and overall congenital cardiac defects, but data are conflicting and limited.

Which is the safest mood stabilizer during pregnancy?

Lamotrigine has been recognized as the overall safest mood stabilizer when both maternal and fetal complications are reviewed.

Does lithium cause miscarriage?

The rate of miscarriage was 16.4% in lithium-exposed pregnancies, versus 8.3% in the bipolar disorder comparison group, and 5.7% in nonteratogenic-exposed pregnancies.

What can I take instead of lithium during pregnancy?

“Over the past couple of decades, lamotrigine has increasingly been used during pregnancy as an alternative treatment option to lithium, due to its more favorable reproductive profile,” wrote the current authors.

Can bipolar medication affect fertility?

Though bipolar disorder does not interfere with your fertility, there are a few things you will want to keep in mind.

What pregnancy category is lithium?

Safety of Psychiatric Medications During Pregnancy and Lactation

Drug FDA pregnancy category*
Lamotrigine (Lamictal) C
Lithium D
Valproic acid (Depakene) D
Antidepressants

How do you deal with bipolar during pregnancy?

Your doctor may suggest that you switch during pregnancy to an older-generation antipsychotic such as haloperidol (Haldol). This may also be a good idea if you’ve stopped taking a mood stabilizer but symptoms came back. Antidepressants.

Can mood stabilizers cause miscarriage?

June 2, 2010 — A Canadian study of more than 5,000 women shows an association between taking antidepressants, particularly the selective serotonin reuptake inhibitors (SSRIs) such as Paxil, Prozac, and Zoloft, and an increased risk for miscarriage.

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Can you take birth control with lithium?

Effects of pharmacotherapy on oral contraceptives

While no drug-drug interactions with OC have been reported to date with valproate, lithium, or the atypical antipsychotics, further study is required in women with bipolar disorder.

Is lithium excreted in breastmilk?

With regard to breastfeeding, lithium is excreted in human breast milk at a mean rate of approximately 50% (range 0.17–1.07%) of the mother serum concentration (Weinstein and Goldfield, 1969; Fries, 1970; Tunnessen and Hertz, 1972; Schou and Amdisen, 1973; Sykes et al., 1976; Viguera et al., 2007; Tanaka et al., 2008).

Is lithium safe for breastfeeding?

Lithium passes easily into babies’ circulation through breastmilk, giving the baby a high level of Lithium in their blood. The National Institute for Health and Care Excellence (2) and the British Association of Psychopharmacology (1) recommend not to breastfeed whilst taking Lithium.

Does lithium cause neural tube defects?

The most serious effect of lithium on nervous system development is the formation of neural tube defects (NTDs). NTDs are a group of severe congenital malformations resulting in a varying degree of disabilities or death.